Blog

Food’s Future: From Production to Consumption

How the NICB is working with industry partner Alltech to tackle sustainable food production The world population is projected to increase to 9.7bn by 2050, placing increasing demands on food production. To meet this requirement, agricultural and animal health industries need to develop innovative solutions for sustainable food production, while considering animal wellbeing, energy and…
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Inspiring New Generations of Scientists – NICB – The Irish-French Connection

BRIDGING THE SCIENCE-TO-SOCIETY GAP FOR THE YOUNGER GENERATIONS On March 16th 2017, the NICB hosted 49 high-school students and 4 teachers coming from the Lycée Jean Jaurès in Châtenay-Malabry, which is located in the suburbs of Paris, France. The visit was organized by two of the teachers, Eve Grandin (English) and Isabelle Bouvier (Biotechnology), and the initiative…
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From Biopharma…to Fantasy Football…and back again

A personal account of making the leap from research to starting a tech company…how I managed to commercialise my invention...and how the startup world looks through a scientist’s eyes This post is about my career and experiences as a research postdoc, followed by my decision to pursue the dream of running my own business and…
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Exploring the unknown – Sequencing the CHO mitochondrial genomic landscape

Recently, we published an article in Metabolic Engineering that revealed widespread genetic heteroplasmy within the mitochondrial genome of Chinese hamster ovary (CHO) cells. That means that every copy of mitochondrial DNA (mtDNA) per cell is not necessarily identical. For the last 30 years, CHO cells have been asked to make hundreds of protein-based therapeutic agents…
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State of the art: Sophisticated production of Biopharmaceuticals

Isolated from the ovary of a Chinese hamster in the 1950s, the Chinese hamster ovary (CHO) cell has become the bedrock of the biopharmaceutical industry. With a projected value of $386.9 billion by the end of 2019, it is the fastest growing sector in Ireland and makes up ~50% of Irish exports per annum. Ireland…
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ESACT Frontiers Retreat in Lyon 2016 – A Great Unusual Scientific Meeting

Between the 20th and the 22nd October, I had the opportunity to attend  the 1st ESACT Frontiers Retreat 2016, taking place in Lyon. Citing words from the organizing committee, this was a non conventional scientific meeting “dedicated to early career scientists working in the cell culture technology field and aimed to engage the next generation…
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miR-acle Grow: Improving CHO cell Growth by miRNA Dysregulation

The “CHO group” here in NICB is a sizable collection of young researchers, incorporating people with a wide variety of cultural and academic backgrounds. Collectively, we effort to tackle many real challenges facing the biopharmaceutical industry today. Some members such as myself, use targeted genetic engineering approaches to improve Chinese Hamster Ovary (CHO) cell characteristics,…
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eCHO Systems – Enhancing the CHO cell factory using Systems Biology

On the 13-14th of September,  the 2nd Annual Meeting for the eCHO Systems Innovative Training Network (ITN)  took place in Vienna. The members of the consortium had the opportunity to meet together with the Scientific Advisory board and the Principal Investigators to discuss the progress made so far and share their future plans for the…
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