Blog

WORLD PANCREATIC CANCER DAY

November 16th 2017 is World Pancreatic Cancer Day .   The aim of this day, which is spearheaded by a coalition of organisations worldwide, is to raise awareness of one of the toughest cancers.     The Pancreatic Cancer Research Group are studying this aggressive disease.   In the NICB, DCU the Pancreatic Cancer Research Group…
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Optimizing Recombinant Protein Production in Cultured Mammalian Cells

This blog is about my research as a Professor of Nanobioscience (SUNY Polytechnic Institute, Albany, NY USA) and Fulbright Visiting Scholar at the NICB, DCU (Sept.-Dec. 2017) and which is summarised in the below video of my talk “Understanding the factors that control productivity in CHO cells” which I delivered in the NICB on Tuesday…
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NICB Cancer Week 2017 Symposium – A snapshot of our research

Cancer Week Ireland is the brain child of the Irish Cancer Society and Trinity College Dublin and aims to discuss improvements in cancer treatments, as well as tackling the physical and emotional consequences that a cancer diagnosis can bring. Cancer research at National Institute for Cellular Biotechnology (NICB) aims to understand human cancer and how…
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Food’s Future: From Production to Consumption

How the NICB is working with industry partner Alltech to tackle sustainable food production The world population is projected to increase to 9.7bn by 2050, placing increasing demands on food production. To meet this requirement, agricultural and animal health industries need to develop innovative solutions for sustainable food production, while considering animal wellbeing, energy and…
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Inspiring New Generations of Scientists – NICB – The Irish-French Connection

BRIDGING THE SCIENCE-TO-SOCIETY GAP FOR THE YOUNGER GENERATIONS On March 16th 2017, the NICB hosted 49 high-school students and 4 teachers coming from the Lycée Jean Jaurès in Châtenay-Malabry, which is located in the suburbs of Paris, France. The visit was organized by two of the teachers, Eve Grandin (English) and Isabelle Bouvier (Biotechnology), and the initiative…
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From Biopharma…to Fantasy Football…and back again

A personal account of making the leap from research to starting a tech company…how I managed to commercialise my invention...and how the startup world looks through a scientist’s eyes This post is about my career and experiences as a research postdoc, followed by my decision to pursue the dream of running my own business and…
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Exploring the unknown – Sequencing the CHO mitochondrial genomic landscape

Recently, we published an article in Metabolic Engineering that revealed widespread genetic heteroplasmy within the mitochondrial genome of Chinese hamster ovary (CHO) cells. That means that every copy of mitochondrial DNA (mtDNA) per cell is not necessarily identical. For the last 30 years, CHO cells have been asked to make hundreds of protein-based therapeutic agents…
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State of the art: Sophisticated production of Biopharmaceuticals

Isolated from the ovary of a Chinese hamster in the 1950s, the Chinese hamster ovary (CHO) cell has become the bedrock of the biopharmaceutical industry. With a projected value of $386.9 billion by the end of 2019, it is the fastest growing sector in Ireland and makes up ~50% of Irish exports per annum. Ireland…
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