Blog

Leachables from disposable bioreactors: Sucking the blood from Biopharma

The future of biopharmaceutical manufacturing platforms is to implement the use of small-scale disposable single-use (SU) plastic wave-reactor bags in parallel to the commonly used 10,000 L stainless steel bioreactors. This will see the industry undergo a facelift with both large multi-billion dollar facilities and smaller, more flexible, sites being constructed with the ability to…
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What is a Monoclonal Antibody?

Originally discovered by Emil Von Bering and Paul Erhlich, antibodies are proteins produced by the immune system that target a specific foreign object (antigen). They are called monoclonal Antibodies (mAbs) when they are produced by clones derived from a single parent cell. Monoclonal antibodies have a high affinity for their epitope, the specific site of…
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A DRIVE towards enhanced Diabetes Treatment

The DRIVE (Diabetes Reversing Implants with enhanced Viability and long-term Efficacy) consortium met recently in Venice Italy for its second general assembly to discuss progress, challenges and plans going forward for achieving their goal of improved Diabetes treatment. Diabetes type 1 is a chronic condition characterised by loss of insulin-producing pancreatic β-cells and an inability…
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The First Cornea-Limbal Stem Transplant in Ireland

On Tuesday morning 07.06.2016, Mr. William Power, Consultant Ophthalmic Surgeon, conducted the very first cornea-limbal stem cell transplant in Ireland, at the Royal Victoria Eye & Ear Hospital, an event that was covered by RTE. Mr. Patrick Godfrey of Co Tipperary underwent the procedure during an hour-long operation in an attempt to restore his deteriorating…
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Telling it straight – How selenium helps prevent cancer

‘Explain your research and its importance to a ‘lay audience’ (aka non-scientists) in a concise and dynamic way, in five minutes’. Sounds simple, right? ‘Telling it straight’, however, proved much trickier than first anticipated. This DCU-run competition challenges post-graduates to communicate their research to an audience and panel of judges that have no prior knowledge…
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Merging Cells And Process: The Path Towards High-Productivity

Improving cell-line productivity is one of the major goals for the CHO group at the National Institute for Cellular Biotechnology (NICB), DCU. Under the supervision of Dr. Niall Barron (CHO Cell Engineering), Dr. Paula Meleady (CHO Proteomics) and Prof.  Martin Clynes (CHO cell biology), CHO researchers combine state-of-the art technologies in molecular biology, proteomics and bioinformatics to develop improved cell-lines in…
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New Treatment for Cornea Blindness at NICB

By the end of the year, it is expected that the first cornea-limbal stem cell transplant in Ireland will have been performed. This is the result of collaboration between researchers, scientists and clinicians in the National Institute for Cellular Biotechnology (NICB) in Dublin City University (DCU), the Royal Victoria Eye and Ear Hospital (RVEEH)and the…
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Tackling Pancreatic Cancer Together

The innovative research undertaken by the pancreatic research group here in NICB, DCU was recently positively reviewed in a fantastic feature by a leading biomedical trade journal, “Academic Pharmacy Now”, focusing in particular on our collaborator and friend, Prof Robert Straubinger. Prof Straubinger’s lab in University at Buffalo is part of a tremendous collaborative initiative between…
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