Portfolio Category: Tissue Engineering & Stem Cell Research

Interaction of Metals with Cells

Interaction of Metals with Cells We are studying the uptake of trace elements and metals such as Iron, Copper, Zinc, Manganese and Selenium by in vitro differentiated models of intestinal epithelium. These trace elements are essential micronutrients, and we are comparing the impact of both inorganic and bound organic forms on the transcriptome and proteome…
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Ocular Diseases

Ocular Diseases The Tissue Engineering & Stem Cell Research programme is involved in research on ocular diseases. The cornea is the transparent dome on the front of the eye that covers the iris (the coloured part of the eye) and the pupil. This transparent dome acts like a window, protecting the iris and the light-detecting…
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Pancreatic Islet Transplantation

Pancreatic Islet Transplantation for the Treatment of Diabetes Approximately 2-3% of the Irish population suffer from diabetes. Type I diabetes (Insulin-dependent diabetes Mellitus, IDDM) is caused by insulin deficiency resulting from autoimmune destruction of the B-cells of the islets of Langerhans in the pancreas. A relatively new treatment for this type of diabetes is to…
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Tissue Engineering & Stem Cell Research

There is tremendous interest at the moment in the potential of tissue engineering/stem cell therapy to cure tissue damage and degeneration, particularly in disease areas where there has been irretrievable loss of tissue, and drug therapies are ineffective. The NICB is directly involved in work leading on to clinical application for corneal stem cell transplant…
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