- Director of the Oxford Islet Isolation and Transplantation Programmes
- Professor of Paediatric Surgery, University of Oxford; Academic Training
- Programme Director for Surgery
Paul qualified in Medicine from the University of Leicester and subsequently trained in General Surgery in Leicester and Derby, followed by Specialist Training in Paediatric Surgery in Oxford, Melbourne and Great Ormond Street Hospital in London. Between 1993 and 1996 he was a Research Fellow in the Department of Surgery at the University of Leicester, where he undertook a project on the ‘Optimisation of the isolation of human islets of Langerhans’. This led to his Doctorate thesis and started his on-going interest in the fields of islet isolation and islet transplantation. He was awarded a Hunterian Professorship from the Royal College of Surgeons of England for this research in 1998.
He currently leads an active research group encompassing basic, translational, and clinical research, with the ultimate goal of making islet transplantation applicable to children. His basic research specifically focuses on: 1) understanding the molecular structure and interactions of the pancreatic matrix (with special emphasis on optimising islet isolation and islet function/engraftment); 2) developing strategies for islet immunoisolation (islet macroencapsulation, islet pre-conditioning, and novel culture / scaffolds).
Paul is Immediate Past-President of the International Pancreas and Islet Transplant Association (IPITA). He has chaired / sat on a number of Research Advisory Boards, including those of British Association of Paediatric Surgeons, DRWF UK, DRWF Sweden, and the Royal College of Surgeons of England. He sits on the UK Pancreas Advisory Group and is Chair of the Islet Isolation Sub-Group of the UK Islet Transplant Consortium. His Group are funded as the JDRF UK Islet Resource Centre for provision of human islets for research.