Translational Research

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  • Translational Cancer Genomic Research

    Translational Cancer Genomic Research

    Cancer is a disease of the genome. Genomic somatic mutations and alterations can change the function of genes, either promoting…

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  • Cancer Biotherapeutics

    Cancer Biotherapeutics

    Biotherapeutics (biologics or biotech drugs) are at the forefront of modern cancer chemotherapy. Examples include the monoclonal antibodies Herceptin ®,…

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  • Targeted Therapies for Cancer

    Targeted Therapies for Cancer

    The Targeted Therapies for Cancer research is focused on two key areas: i) preclinical evaluation of novel targeted therapies in…

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  • 3U Diabetes Consortium

    3U Diabetes Consortium

    Diabetes at the NICB: 3U Partnership The 3U Partnership is a major strategic initiative that combines the research expertise of…

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  • Diabetes

    Diabetes

    Diabetes is the fastest growing chronic disease with global prevalence having increased from 30 million in 1985 to 220 million…

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  • Interaction of Metals with Cells

    Interaction of Metals with Cells

    Interaction of Metals with Cells We are studying the uptake of trace elements and metals such as Iron, Copper, Zinc,…

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  • Ocular Diseases

    Ocular Diseases

    Ocular Diseases The Tissue Engineering & Stem Cell Research programme is involved in research on ocular diseases. The cornea is…

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  • Pancreatic Islet Transplantation

    Pancreatic Islet Transplantation

    Pancreatic Islet Transplantation for the Treatment of Diabetes Approximately 2-3% of the Irish population suffer from diabetes. Type I diabetes…

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  • Uveal Melanoma

    Uveal Melanoma

    Uveal Melanoma Research Using Proteomic Methods Uveal melanoma is the most common intraocular malignancy in adults. The survival rate of…

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  • Pancreatic Cancer

    Pancreatic Cancer

    Pancreatic Cancer Research Programme The pancreatic research programme focuses on understanding the molecular mechanisms of drug resistance, invasion and metastasis…

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  • Novel ADC targets & Monoclonal antibodies

    Novel ADC targets & Monoclonal antibodies

    Novel ADC targets & Monoclonal Antibodies for Biopharmaceuticals Therapeutic antibodies are the largest class of biopharmaceuticals for human disease. Development…

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  • Multiple Myeloma

    Multiple Myeloma

    Multiple Myeloma - Personalized Medicine Personalized Medicine in practice; Discovery of Potential Proteomic Biomarkers For Predicting the Drug Response in…

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  • Lung Cancer

    Lung Cancer

    Lung cancer is the second most common cancer in men and women (excluding skin cancer) in the US and third…

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  • Drug Resistance in Cancers

    Drug Resistance in Cancers

    Drug Resistance in Cancers The NICB has developed a range of human cell models for resistance to chemotherapeutic agents (contact:…

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  • Molecular Therapeutics for Cancer

    Molecular Therapeutics for Cancer

    Under the leadership of Prof John Crown, the Molecular Therapeutics for Cancer research programme aims to investigate response and resistance…

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  • Biomarkers

    Biomarkers

    Biomarkers for Protein Characterisation A biomarker is a substance used as an indicator of a biologic state, and that is…

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  • Cancer

    Cancer

    Cancer research at NICB aims to apply the powerful techniques associated with cell and molecular biology to gaining a deeper…

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  • Tissue Engineering & Stem Cell Research

    Tissue Engineering & Stem Cell Research

    There is tremendous interest at the moment in the potential of tissue engineering/stem cell therapy to cure tissue damage and…

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  • Chemical Synthesis & Chemical Biology

    Chemical Synthesis & Chemical Biology

    The NICB Synthetic Chemistry group is involved in the development and application of targeted molecular libraries and is now increasingly…

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