Flow Cytometry Core Facility Manager

Postdoctoral Research Fellow

Diabetes Group

Phone: +353 (01) 7005402
Email: clair.gallagher@dcu.ie
Linkedin
Researchgate

Academic background:

  • BSc Applied Biology with Quality Management
  • MSc Bioinformatics
  • PhD “Multiplex PCR Suspension Array Method Development for High-Throughput NIDDM Disease Association.”

 

Principal Research Interests: 

  • Chinese Hamster Ovary (CHO) cell biology biopharmaceutical research
  • Stem cells for treatment of Diabetes Type 1
  • Pancreatic islet isolation for the treatment of Diabetes Type 1
  • Stem cells for ocular regeneration
  • Ocular stem cells for therapeutic application
  • Enhanced wound-healing strategies for corneal and dermal repair

 

Publications:

  1. Kelly PS, Gallagher C, Clynes M, Barron N. Conserved microRNA function as a basis for Chinese hamster ovary cell engineering. Biotechnol Lett. 2015;37:787-798.
  2. Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J. 2015;10:1029-1040.
  3. Monger C, Kelly PS, Gallagher C, Clynes M, Barron N, Clarke C. Towards next generation CHO cell biology: Bioinformatics methods for RNA-Seq-based expression profiling. Biotechnol J. 2015;10:950-966.
  4. Browne, C. Surlis, A Maher, C. Gallagher et al. Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection. Virulence. 2015
  5. Kelly, C. Gallagher, M. Clynes, N. Barron. Conserved microRNA function as a basis for Chinese hamster ovary cell engineering. Biotechnol Lett. 2014.
  6. McMahon, C. Gallagher, N. O’Reilly, M. Clynes, F. O’Sullivan, K. Kavanagh. Exposure of a corneal epithelial cell line (hTCEpi) to Demodex-associated Bacillus proteins results in an inflammatory response. Invest Ophthalmol Vis Sci. 2014;55(10):7019-28.
  7. Gallagher, C. Clarke, S. T. Aherne, K. Katikireddy, P. Doolan, V. Lynch, S. Shaw, A. Bobart-Hone, C. C. Murphy, M. Clynes, W. Power, and F. O’Sullivan, Comparative transcriptomic analysis of cultivated limbal epithelium and donor corneal tissue reveals altered wound healing gene expression., Invest. Ophthalmol. Vis. Sci., 2014.
  8. Sanchez, P. Kelly, C. Gallagher, N. T. Lao, C. Clarke, M. Clynes, and N. Barron, CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors, Biotechnol. J., vol. 9, pp. 396–404, 2014.
  9. Sanchez, M. Gallagher, N. Lao, C. Gallagher, C. Clarke, P. Doolan, S. Aherne, A. Blanco, P. Meleady, M. Clynes, and N. Barron, MiR-7 Triggers Cell Cycle Arrest at the G1/S Transition by Targeting Multiple Genes Including Skp2 and Psme3, PLoS One, vol. 8, 2013.
  10. O’Reilly, C. Gallagher, K. Reddy Katikireddy, M. Clynes, F. O’Sullivan, and K. Kavanagh, Demodex-associated Bacillus proteins induce an aberrant wound healing response in a corneal epithelial cell line: possible implications for corneal ulcer formation in ocular rosacea., Invest. Ophthalmol. Vis. Sci., vol. 53, pp. 3250–3259, 2012.
  11. C. Mansergh, R. Vawda, S. Millington-Ward, P. F. Kenna, J. Haas, C. Gallagher, J. H. Wilson, P. Humphries, M. Ader, and G. J. Farrar, Loss of photoreceptor potential from retinal progenitor cell cultures, despite improvements in survival, Exp. Eye Res., vol. 91, pp. 500–512, 2010.
Share

EnglishJapanese