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Translational Cancer Genomic Research
Cancer is a disease of the genome. Genomic somatic mutations and alterations can change the function of genes, either promoting…
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Cancer Biotherapeutics
Biotherapeutics (biologics or biotech drugs) are at the forefront of modern cancer chemotherapy. Examples include the monoclonal antibodies Herceptin ®,…
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Targeted Therapies for Cancer
The Targeted Therapies for Cancer research is focused on two key areas: i) preclinical evaluation of novel targeted therapies in…
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3U Diabetes Consortium
Diabetes at the NICB: 3U Partnership The 3U Partnership is a major strategic initiative that combines the research expertise of…
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Interaction of Metals with Cells
Interaction of Metals with Cells We are studying the uptake of trace elements and metals such as Iron, Copper, Zinc,…
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Ocular Diseases
Ocular Diseases The Tissue Engineering & Stem Cell Research programme is involved in research on ocular diseases. The cornea is…
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Pancreatic Islet Transplantation
Pancreatic Islet Transplantation for the Treatment of Diabetes Approximately 2-3% of the Irish population suffer from diabetes. Type I diabetes…
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Uveal Melanoma
Uveal Melanoma Research Using Proteomic Methods Uveal melanoma is the most common intraocular malignancy in adults. The survival rate of…
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Pancreatic Cancer
Pancreatic Cancer Research Programme The pancreatic research programme focuses on understanding the molecular mechanisms of drug resistance, invasion and metastasis…
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Novel ADC targets & Monoclonal antibodies
Novel ADC targets & Monoclonal Antibodies for Biopharmaceuticals Therapeutic antibodies are the largest class of biopharmaceuticals for human disease. Development…
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Multiple Myeloma
Multiple Myeloma - Personalized Medicine Personalized Medicine in practice; Discovery of Potential Proteomic Biomarkers For Predicting the Drug Response in…
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Lung Cancer
Lung cancer is the second most common cancer in men and women (excluding skin cancer) in the US and third…
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Drug Resistance in Cancers
Drug Resistance in Cancers The NICB has developed a range of human cell models for resistance to chemotherapeutic agents (contact:…
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Molecular Therapeutics for Cancer
Under the leadership of Prof John Crown, the Molecular Therapeutics for Cancer research programme aims to investigate response and resistance…
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Biomarkers
Biomarkers for Protein Characterisation A biomarker is a substance used as an indicator of a biologic state, and that is…
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Tissue Engineering & Stem Cell Research
There is tremendous interest at the moment in the potential of tissue engineering/stem cell therapy to cure tissue damage and…
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Chemical Synthesis & Chemical Biology
The NICB Synthetic Chemistry group is involved in the development and application of targeted molecular libraries and is now increasingly…
