Associate Director, NICB

Tissue Engineering; Stem Cells; Cell Microscopy

Cell Characterisation Facility Manager


Research Groups

Diabetes Group
Stem Cells & Differentiation


Phone:+353 1 7008390
Fax:+353 1 700 5484

Principal Research Interests:

Investigations of Chinese Hamster Ovary (CHO) cell biology as a Means of Cell Line Improvement in Biopharma Production.

Development of limbal-cornea cell culture methods for therapeutic purposes.

Investigations into the mechanisms of Fuchs Dystrophy

Cell differentiation and Stem Cell Biology

Cell-Nanostructure interactions

Selected Publications

  1. McMahon FW, Gallagher C, O'Reilly N, Clynes M, O'Sullivan F, Kavanagh K. (2014) Exposure of a corneal epithelial cell line (hTCEpi) to Demodex-associated Bacillus proteins results in an inflammatory response. Invest Ophthalmol Vis Sci. 2014 Oct 2;55(10):7019-28. doi: 10.1167/iovs.14-15018.
  2. Gallagher C, Clarke C, Aherne ST, Katikireddy KR, Doolan P, Lynch V, Shaw S, Bobart-Hone A, Murphy C, Clynes M, Power W, O'Sullivan F. (2014) Comparative transcriptomic analysis of cultivated limbal epithelium and donor corneal tissue reveals altered wound healing gene expression. Invest Ophthalmol Vis Sci. 2014 Aug 14;55(9):5795-805. doi: 10.1167/iovs.14-14664.
  3. O'Reilly N, Gallagher C, Reddy Katikireddy K, Clynes M, O'Sullivan F, Kavanagh K. (2012) Demodex-associated Bacillus proteins induce an aberrant wound healing response in a corneal epithelial cell line: possible implications for corneal ulcer formation in ocular rosacea. Invest Ophthalmol Vis Sci. 2012 May 31;53(6):3250-9. doi: 10.1167/iovs.11-9295.
  4. O’Sullivan F and Clynes M. (2007) Limbal stem cells a review of their identification and culture for clinical use. Cytotechnology, 53, 101-106.


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